{"id":3865,"date":"2020-04-14T17:12:17","date_gmt":"2020-04-14T14:12:17","guid":{"rendered":"https:\/\/rugute.lt\/?page_id=3865"},"modified":"2022-01-12T09:51:06","modified_gmt":"2022-01-12T07:51:06","slug":"sarkomos","status":"publish","type":"page","link":"https:\/\/rugute.lt\/en\/informacija\/piktybiniai-navikai\/sarkomos\/","title":{"rendered":"Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos"},"content":{"rendered":"
\n\t\t\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t
Piktybiniai navikai<\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Vaik\u0173 mink\u0161t\u0173j\u0173 audini\u0173 sarkomos \u2013 tai grup\u0117 navikini\u0173 susirgim\u0173, kuomet piktybin\u0117s l\u0105stel\u0117s ima nevaldomai ir netvarkingai daugintis mink\u0161tuosiuose audiniuose.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t\t\t\t
\n\t\t\t\t\t\t\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/i>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/i>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tMink\u0161t\u0173j\u0173 audini\u0173 sarkomos\t\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t
\n\t\t\t\t\t\t\t
Mink\u0161tiesiems audiniams priklauso raumenys, sausgysl\u0117s, jungiamasis bei riebalinis audiniai, o taip pat kraujagysl\u0117s, limfagysl\u0117s, nervai ir sinovinis audinys (i\u0161klojantis i\u0161 vidaus s\u0105nari\u0173 kapsules). Apibendrinant – mink\u0161tieji audiniai sujungia ir apsupa kitas k\u016bno dalis bei organus, u\u017etikrina j\u0173 mityb\u0105 ir tinkam\u0105 funkcionavim\u0105.<\/div>
\u00a0<\/div>
\u0160ios sarkomos skirstomos \u012f daugyb\u0119 r\u016b\u0161i\u0173 pagal tai, i\u0161 kokio audinio yra kilusios. Da\u017eniausiai (daugiau kaip 50 % atvej\u0173) vaik\u0173 am\u017eiuje pasirei\u0161kia rabdomiosarkoma. Kitos sarkomos vadinamos nerabdomiosarkomin\u0117mis mink\u0161t\u0173j\u0173 audini\u0173 sarkomomis ir aptariamos skyriaus gale.<\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t
\n\t\t\t\t\t\t\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/i>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/i>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tRabdomiosarkoma\t\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t
\n\t\t\t\t\t\t\t
Tai – piktybinis mink\u0161t\u0173j\u0173 audini\u0173 navikas, kil\u0119s i\u0161 skeleto raumen\u0173. Pagal strukt\u016br\u0105 rabdomiosarkoma skirstoma \u012f embrionin\u0119 (50-70 %) bei alveolin\u0119 (20 %). Kartais i\u0161skiriama ir botrioidin\u0117 (5-10 %) rabdomiosarkoma, kuri yra embrionin\u0117s atmaina. Tumoro r\u016b\u0161is ir lokalizacija priklauso nuo am\u017eiaus. Embrionin\u0117 rabdomiosarkoma da\u017eniausiai i\u0161sivysto vaikams iki 8 m. Paprastai tumoras susidaro galvos ar kaklo srityje. Retesn\u0117 susidarymo vieta \u2013 \u0161lapimo p\u016bsl\u0117, prostata (berniukams), mak\u0161tis (mergait\u0117ms). Paaugliams da\u017enesn\u0117 alveolin\u0117 rabdomiosarkoma, kuri paprastai susidaro gal\u016bn\u0117se, re\u010diau – liemenyje.<\/div>
\u00a0<\/div>
Sergamumas<\/b><\/div>
\u0160i sarkoma gan\u0117tinai reta vaik\u0173 ir paaugli\u0173 am\u017eiuje \u2013 sudaro tik apie 4% vis\u0173 piktybini\u0173 vaik\u0173 navik\u0173. Pus\u0117 ligos atvej\u0173 diagnozuojama iki 5 m. am\u017eiaus. \u0160iek tiek da\u017eniau serga berniukai.<\/div>
\u00a0<\/div>
Prie\u017eastys <\/b><\/div>
Tikimyb\u0119 susirgti rabdomiosarkoma didina kelios paveldimos ligos, tame tarpe Li-Fraumeni sindromas, I tipo neurofibromatoz\u0117, Beckwith-Wiedemann sindromas. Nustatyta, jog embrionin\u0117s rabdomiosarkomos i\u0161sivystym\u0105 lemia geno, esan\u010dio 11 chromosomoje, mutacija (patologinis pokytis). Alveolin\u0117s rabdomiosarkomos atveju randama kita mutacija, vadinama t(2;13) translokacija (genetin\u0117s med\u017eiagos pasikeitimas tarp 2 ir 13 chromosom\u0173).<\/div>
\u00a0<\/div>
Simptomai<\/b><\/div>
Rabdomiosarkomos simptomai priklauso nuo tumoro susidarymo vietos ir naviko i\u0161plitimo. Da\u017eniausiai d\u0117mes\u012f atkreipia atsirad\u0119s kietas darinukas ar guzelis, nesusij\u0119s su trauma. Kiti simptomai gali atsirasti navikui augant ir sutrikdant aplinkini\u0173 strukt\u016br\u0173 funkcij\u0105. Ne taip kaip karcinomos, sarkomos retai kada sukelia kar\u0161\u010diavim\u0105, naktin\u012f prakaitavim\u0105 ar k\u016bno svorio kritim\u0105.<\/div>
\u00a0<\/div>
Pagrindiniai simptomai priklauso nuo pakenkimo lokalizacijos:<\/div>
– akiduob\u0117 \u2013 voko nusileidimas, akies obuolio i\u0161st\u016bmimas, \u017evairumas;<\/div>
– nosis, sinusai \u2013 nosies u\u017egulimas, pakit\u0119s balsas, i\u0161skyros i\u0161 nosies, kraujavimas;<\/div>
– gal\u016bn\u0117s, liemuo – guzelis, skausmingas patinimas, paraudimas;<\/div>
– kr\u016btin\u0117s l\u0105sta \u2013 apsunkintas kv\u0117pavimas, dusulys, l\u0117tinis kosulys;<\/div>
– \u017earnynas – pilvo skausmas, pykinimas ir\/ar v\u0117mimas, viduri\u0173 u\u017ekiet\u0117jimas;<\/div>
– \u0161lapimo p\u016bsl\u0117, prostata \u2013 skausmingas, apsunkintas \u0161lapinimasis, kraujas \u0161lapime;<\/div>
– s\u0117klid\u017ei\u0173 sritis (berniukams) \u2013 padid\u0117j\u0119s, patin\u0119s kap\u0161elis;<\/div>
– mak\u0161tis, gimdos kaklelis, gimda (mergait\u0117ms) \u2013 i\u0161skyros, kraujavimas i\u0161 i\u0161orini\u0173 lytini\u0173 organ\u0173, pilvo apa\u010dios, dubens skausmas.<\/div>
\u00a0<\/div>
Diagnostika<\/b><\/div>
Norint diagnozuoti lig\u0105, atliekami sekantys tyrimai:<\/div>
– klinikinis kraujo tyrimas;<\/div>
– biocheminis kraujo tyrimas (kepen\u0173 fermentai, elektrolitai);<\/div>
– kontrastin\u0117 kompiuterin\u0117 tomografija, kai kada \u2013 magnetinio rezonanso tomografija ar pozitronin\u0117s emisijos tomografija (PET);<\/div>
– tumoro biopsija (audinio gabal\u0117lio pa\u0117mimas i\u0161tyrimui mikroskopu bei molekulin\u0117s biologijos metodais);<\/div>
– tyrimai, reikalingi naviko i\u0161plitimui nustatyti (kaul\u0173 \u010diulp\u0173 aspiracija ir biopsija, radioizotopinis kaul\u0173 skenavimas, ultragarsinis pilvo tyrimas, juosmenin\u0117 punkcija ir kt.).<\/div>
\u00a0<\/div>
Priklausomai nuo pradin\u0117s tumoro vietos, i\u0161plitimo \u012f aplinkinius ir atokius organus, nustatoma ligos stadija.<\/div>
\u00a0<\/div>
Gydymas<\/b><\/div>
Rabdomiosarkomos atveju taikomas kombinuotas gydymas, susidedantis i\u0161 chirurginio, spindulinio gydymo bei chemoterapijos. Diagnoz\u0117s nustatymo metu tik 10 % vaik\u0173 tumoras gali b\u016bti pa\u0161alintas visi\u0161kai, tod\u0117l visuomet taikoma chemoterapija, o dauguma atvej\u0173 \u2013 ir spindulinis gydymas. Netaikant spindulinio gydymo, 50% tikimyb\u0117, jog navikas pakartotinai susidarys toje pa\u010dioje vietoje, netaikant chemoterapijos \u2013 80 % tikimyb\u0117, jog atsiras metastaz\u0117s.<\/div>
\u00a0<\/div>
Chirurginis gydymas<\/i><\/div>
Visi vaikai, kuriems nustatoma rabdomiosarkoma, yra kuo anks\u010diau operuojami, stengiantis pa\u0161alinti vis\u0105 navik\u0105 kartu su j\u012f supan\u010diais sveikais audiniais. Po operacijos, pa\u0161alinta med\u017eiaga siun\u010diama i\u0161tyrimui mikroskopu, siekiant nustatyti, ar navikas i\u0161pjautas sveik\u0173 audini\u0173 ribose. Kartais, kuomet navikas peraug\u0119s gyvybi\u0161kai svarbias kraujagysles ar giliai i\u0161plit\u0119s \u012f aplinkinius audinius, nuo visi\u0161kos rezekcijos susilaikoma. Po chemoterapijos neretai atliekamos antrin\u0117s operacijos, kuri\u0173 metu pa\u0161alinami tumoro liku\u010diai ir \u012fvertinama, ar reikalingas tolimesnis spindulinis gydymas.<\/div>
\u00a0<\/div>
Chemoterapija<\/i><\/div>
Sergant rabdomiosarkoma, po naviko pa\u0161alinimo neskiriant chemoterapijos, dauguma vaik\u0173 mirt\u0173 d\u0117l metastazi\u0173, nes diagnoz\u0117s nustatymo metu jos b\u016bna daugeliui, ta\u010diau per ma\u017eos, kad b\u016bt\u0173 galima aptikti \u012fprastiniais tyrimo metodais. Chemoterapija taikoma ir prie\u0161 operacij\u0105, siekiant, jog pirminis navikas suma\u017e\u0117t\u0173. Da\u017eniausiai gydymui naudojamas vinkristinas, aktinomicinas D, ifosfamidas, ciklofosfamidas, etopozidas bei doksorubicinas. \u012e gydymo protokolus vis da\u017eniau \u012ftraukiami ir naujieji topoizomeraz\u0117s-I inhibitoriai – topotekanas ir irinotekanas. Kadangi gydymui taikomos didel\u0117s vaist\u0173 doz\u0117s, siekiant suma\u017einti pa\u0161alin\u012f j\u0173 poveik\u012f, papildomai skiriami apsauginiai medikamentai \u2013 Mesna, granuliocit\u0173 kolonijas stimuliuojantis faktorius ir kt. (\u017er. \u201eChemoterapija\u201c).<\/div>
\u00a0<\/div>
Spindulinis gydymas<\/i><\/div>
I\u0161orinis spindulinis gydymas naudojamas nepavykus visi\u0161kai pa\u0161alinti naviko operacijos metu bei sunaikinti taikant chemoterapij\u0105. Nusta\u010dius kaukol\u0117s, smegen\u0173 dangal\u0173 ar nugaros smegen\u0173 navik\u0105, spindulinis gydymas pradedamas nedelsiant.<\/div>
\u00a0<\/div>
Kaul\u0173 \u010diulp\u0173 ir kamienini\u0173 l\u0105steli\u0173 transplantacija<\/i><\/div>
Kamienini\u0173 l\u0105steli\u0173 transplantacija \u2013 viena i\u0161 naujausi\u0173 rabdomiosarkomos gydymo alternatyv\u0173. Taikoma agresyvi chemoterapija didel\u0117mis doz\u0117mis, kurios metu sunaikinamos navikin\u0117s l\u0105stel\u0117s, ta\u010diau kartu \u017e\u016bsta ir kaul\u0173 \u010diulpai. Jiems i\u0161 naujo u\u017epildyti panaudojamos anks\u010diau i\u0161 kraujo surinktos periferin\u0117s kamienin\u0117s l\u0105stel\u0117s.<\/div>
\u00a0<\/div>
Prognoz\u0117<\/b><\/div>
Tikimyb\u0117 pasveikti priklauso nuo naviko lokalizacijos, histologinio tipo, ligos stadijos, galimyb\u0117s tumor\u0105 pa\u0161alinti chirurgi\u0161kai, paciento am\u017eiaus bei gretutini\u0173 lig\u0173.<\/div>
\u00a0<\/div>
Esant nedideliam ribotam tumorui, i\u0161gyvenamumas yra apie 80 %. Jeigu navikas didelis ir jo negalima i\u0161 karto pa\u0161alinti, i\u0161gyvenamumas siekia apie 50 %. Prognoz\u0117 n\u0117ra gera (20-30 %), jei navikas yra i\u0161plit\u0119s \u012f kitas k\u016bno sritis (metastazav\u0119s). Kadangi alveolinis rabdomiosarkomos tipas yra agresyviausias, j\u012f nusta\u010dius, prognoz\u0117 kiek blogesn\u0117 nei esant embrioninei (ar botrioidinei) rabdomiosarkomai.<\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t
\n\t\t\t\t\t\t\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/i>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/i>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tKitos mink\u0161t\u0173j\u0173 audini\u0173 sarkomos\t\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t
\n\t\t\t\t\t\t\t
Visos nerabdomiosarkomin\u0117s mink\u0161t\u0173j\u0173 audini\u0173 sarkomos sudaro 3 % piktybini\u0173 vaik\u0173 navik\u0173.<\/div>
\u00a0<\/div>
Priklausomai nuo kilm\u0117s jos skirstomos:<\/div>
\u00a0<\/div>
Raumeninis audinys<\/i><\/div>
– lejomiosarkoma – i\u0161 lygi\u0173j\u0173 raumen\u0173 l\u0105steli\u0173.<\/div>
\u00a0<\/div>
Jungiamasis audinys<\/i><\/div>
– fibromatoz\u0117s, kitaip – desmoidiniai tumorai;<\/div>
– suaugusi\u0173j\u0173 ir k\u016bdiki\u0173 fibrosarkoma;<\/div>
– dermatofibrosarkoma;<\/div>
– piktybin\u0117 fibrozuojanti histiocitoma.<\/div>
\u00a0<\/div>
Riebalinis audinys<\/i><\/div>
– liposarkoma.<\/div>
\u00a0<\/div>
Kraujagyslinis audinys<\/i><\/div>
– angiosarkoma – i\u0161 kraujagysli\u0173 l\u0105steli\u0173;<\/div>
– limfangiosarkoma – i\u0161 limfagysli\u0173 l\u0105steli\u0173;<\/div>
– hemangiopericitoma – i\u0161 pericit\u0173 – l\u0105steli\u0173, supan\u010di\u0173 smulkias kraujagysles;<\/div>
– hemangioendotelioma – i\u0161 kraujagysli\u0173 vidin\u012f sluoksn\u012f, endotel\u012f, sudaran\u010di\u0173 l\u0105steli\u0173.<\/div>
\u00a0<\/div>
Nervinis audinys<\/i><\/div>
– piktybin\u0117 \u0161vanoma, kitaip – neurofibrosarkoma – i\u0161 nervines skaidulas supan\u010di\u0173 dangal\u0173 l\u0105steli\u0173.<\/div>
\u00a0<\/div>
Kaulinis ir kremzlinis audinys<\/i><\/div>
– ekstraosalin\u0117 (nekaulin\u0117) osteosarkoma – i\u0161 kaulini\u0173 l\u0105steli\u0173;<\/div>
– ekstraosalin\u0117 (nekaulin\u0117) miksoidin\u0117 ir mezenchimin\u0117 chondrosarkoma – i\u0161 kremzlini\u0173 l\u0105steli\u0173.<\/div>
\u00a0<\/div>
Keli\u0173 audini\u0173 navikai<\/i><\/div>
– piktybin\u0117 mezenchimoma;<\/div>
– piktybinis Tritono navikas – turi piktybin\u0117s \u0161vanomos ir rabdomiosarkomos element\u0173.<\/div>
\u00a0<\/div>
Neai\u0161kios kilm\u0117s navikai<\/i><\/div>
– alveolin\u0117 mink\u0161t\u0173j\u0173 audini\u0173 sarkoma, kitaip – piktybin\u0117 granuliozin\u0117 mioblastoma (angl. alveolar soft part sarkoma);<\/div>
– epitelioidin\u0117 sarkoma;<\/div>
– skaidri\u0173 l\u0105steli\u0173 sarkoma, kitaip \u2013 piktybin\u0117 mink\u0161t\u0173j\u0173 audini\u0173 melanoma (angl. clear cell sarkoma);<\/div>
– sinovin\u0117 sarkoma (i\u0161sivysto ne i\u0161 sinovinio dangalo, grei\u010diausiai i\u0161 jungiamojo audinio pirmtakini\u0173 l\u0105steli\u0173);<\/div>
– desmoplastinis apvali\u0173 ma\u017e\u0173 m\u0117lyn\u0173 l\u0105steli\u0173 navikas.<\/div>
\u00a0<\/div>
I\u0161 \u0161i\u0173 sarkom\u0173 vaik\u0173 am\u017eiuje da\u017eniausios – sinovin\u0117 sarkoma, fibrosarkoma, piktybin\u0117 fibrozuojanti histiocitoma ir piktybin\u0117 \u0161vanoma, kitaip \u2013 neurofibrosarkoma.<\/div>
\u00a0<\/div>
Sinovin\u0117 sarkoma<\/b><\/div>
Da\u017eniausiai ji randama paaugliams ir labai retai diagnozuojama iki 10 m. am\u017eiaus. Paprastai tumoras susidaro kojose, ypa\u010d \u0161launies ar kelio srityje. Retesn\u0117s vietos \u2013 rankos, galva, kaklas ir liemuo.<\/div>
\u00a0<\/div>
Fibrosarkoma<\/b><\/div>
Tai da\u017eniausia nerabdomiosarkomin\u0117 mink\u0161t\u0173j\u0173 audini\u0173 sarkoma vaikams iki 1 m. am\u017eiaus. Paprastai serga vaikai iki 5 m. bei 10-15 m. am\u017eiaus. Da\u017eniausiai susidaro gal\u016bn\u0117se. Diagnoz\u0117s nustatymo metu navikas retai b\u016bna i\u0161plit\u0119s, tod\u0117l prognoz\u0117 gera.<\/div>
\u00a0<\/div>
Piktybin\u0117 \u0161vanoma<\/b><\/div>
\u0160is agresyvus auglys sudaro 5-10 % vis\u0173 nerabdomiosarkomini\u0173 mink\u0161t\u0173j\u0173 audini\u0173 sarkom\u0173. Pasteb\u0117tas ry\u0161ys su paveldima liga \u2013 neurofibromatoze. Da\u017eniausiai susidaro rankose ar kojose.<\/div>
\u00a0<\/div>
Piktybin\u0117 fibrozuojanti histiocitoma<\/b><\/div>
\u0160is navikas da\u017eniausiai susidaro kojose bei liemenyje, re\u010diau \u2013 rankose, skalpe, inkstuose.<\/div>
\u00a0<\/div>
Simptomai<\/b><\/div>
Paprastai, \u0161ios sarkomos pastebimos kaip neskausmingi guzeliai \u012fvairiose k\u016bno vietose, da\u017eniausiai sutrikdantys aplinkini\u0173 strukt\u016br\u0173 funkcij\u0105. Tyrimai nesiskiria nuo rabdomiosarkomos, tiksli\u0105 diagnoz\u0119 patvirtina biopsija (\u017er. \u201eRabdomiosarkoma\u201c).<\/div>
\u00a0<\/div>
Gydymas<\/b><\/i><\/div>
<\/i>Pasirenkant gydym\u0105, labiausiai atsi\u017evelgiama \u012f tumoro dyd\u012f ir lokalizacij\u0105, o ne mikroskopin\u0119 sandar\u0105 (histologij\u0105). Da\u017eniausiai taikomas chirurginis gydymas, kai kada j\u012f kombinuojant su spinduliniu. Chemoterapija gali b\u016bti panaudojama siekiant suma\u017einti pradin\u012f naviko dyd\u012f prie\u0161 operacij\u0105. Operuojant gal\u016bni\u0173 navikus, jei tik \u012fmanoma, stengiamasi gal\u016bn\u0119 i\u0161saugoti, kartais tenka atlikti ir amputacij\u0105 (\u017er. \u201eKaul\u0173 sarkomos\u201c). Prognoz\u0119 lemia galimyb\u0117 navik\u0105 pa\u0161alinti visi\u0161kai. Ret\u0173 mink\u0161t\u0173j\u0173 audini\u0173 sarkom\u0173 atveju ma\u017ei vaikai gydomi remiantis rabdomiosarkomos gydymo protokolais, o paaugliai \u2013 tos r\u016b\u0161ies sarkom\u0173 gydymo protokolais, skirtais suaugusiems<\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Piktybiniai navikai Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos Vaik\u0173 mink\u0161t\u0173j\u0173 audini\u0173 sarkomos \u2013 tai grup\u0117 navikini\u0173 susirgim\u0173, kuomet piktybin\u0117s l\u0105stel\u0117s ima nevaldomai ir netvarkingai daugintis mink\u0161tuosiuose audiniuose. Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos Mink\u0161tiesiems audiniams priklauso raumenys, sausgysl\u0117s, jungiamasis bei riebalinis audiniai, o taip pat kraujagysl\u0117s, limfagysl\u0117s, nervai ir sinovinis audinys (i\u0161klojantis i\u0161 vidaus s\u0105nari\u0173 kapsules). Apibendrinant \u2013 mink\u0161tieji audiniai sujungia […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":3842,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-3865","page","type-page","status-publish","hentry"],"yoast_head":"\nMink\u0161t\u0173j\u0173 audini\u0173 sarkomos - Labdaros ir paramos fondas \u201eRugut\u0117\u201c<\/title>\n<meta name=\"description\" content=\"Vaik\u0173 mink\u0161t\u0173j\u0173 audini\u0173 sarkomos \u2013 tai grup\u0117 navikini\u0173 susirgim\u0173, kuomet piktybin\u0117s l\u0105stel\u0117s ima nevaldomai daugintis...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rugute.lt\/en\/informacija\/piktybiniai-navikai\/sarkomos\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos - Labdaros ir paramos fondas \u201eRugut\u0117\u201c\" \/>\n<meta property=\"og:description\" content=\"Vaik\u0173 mink\u0161t\u0173j\u0173 audini\u0173 sarkomos \u2013 tai grup\u0117 navikini\u0173 susirgim\u0173, kuomet piktybin\u0117s l\u0105stel\u0117s ima nevaldomai daugintis...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/rugute.lt\/en\/informacija\/piktybiniai-navikai\/sarkomos\/\" \/>\n<meta property=\"og:site_name\" content=\"Labdaros ir paramos fondas \u201eRugut\u0117\u201c\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/rugute\/\" \/>\n<meta property=\"article:modified_time\" content=\"2022-01-12T07:51:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/rugute.lt\/wp-content\/uploads\/2019\/01\/rugute_logo_uzrasas.png\" \/>\n\t<meta property=\"og:image:width\" content=\"2000\" \/>\n\t<meta property=\"og:image:height\" content=\"646\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@rugute\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":[\"WebPage\",\"MedicalWebPage\"],\"@id\":\"https:\\\/\\\/rugute.lt\\\/informacija\\\/piktybiniai-navikai\\\/sarkomos\\\/\",\"url\":\"https:\\\/\\\/rugute.lt\\\/informacija\\\/piktybiniai-navikai\\\/sarkomos\\\/\",\"name\":\"Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos - Labdaros ir paramos fondas \u201eRugut\u0117\u201c\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/rugute.lt\\\/#website\"},\"datePublished\":\"2020-04-14T14:12:17+00:00\",\"dateModified\":\"2022-01-12T07:51:06+00:00\",\"description\":\"Vaik\u0173 mink\u0161t\u0173j\u0173 audini\u0173 sarkomos \u2013 tai grup\u0117 navikini\u0173 susirgim\u0173, kuomet piktybin\u0117s l\u0105stel\u0117s ima nevaldomai daugintis...\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/rugute.lt\\\/informacija\\\/piktybiniai-navikai\\\/sarkomos\\\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/rugute.lt\\\/informacija\\\/piktybiniai-navikai\\\/sarkomos\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/rugute.lt\\\/informacija\\\/piktybiniai-navikai\\\/sarkomos\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Prad\u017eia\",\"item\":\"https:\\\/\\\/rugute.lt\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Informacija\",\"item\":\"https:\\\/\\\/rugute.lt\\\/informacija\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Piktybiniai navikai\",\"item\":\"https:\\\/\\\/rugute.lt\\\/informacija\\\/piktybiniai-navikai\\\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/rugute.lt\\\/#website\",\"url\":\"https:\\\/\\\/rugute.lt\\\/\",\"name\":\"Labdaros ir paramos fondas \u201eRugut\u0117\u201c\",\"description\":\"Parama vaikams sergantiems v\u0117\u017eiu\",\"publisher\":{\"@id\":\"https:\\\/\\\/rugute.lt\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/rugute.lt\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/rugute.lt\\\/#organization\",\"name\":\"Labdaros ir paramos fondas \u201eRugut\u0117\u201c\",\"url\":\"https:\\\/\\\/rugute.lt\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/rugute.lt\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/rugute.lt\\\/wp-content\\\/uploads\\\/2021\\\/09\\\/Rugute_logo-b.svg\",\"contentUrl\":\"https:\\\/\\\/rugute.lt\\\/wp-content\\\/uploads\\\/2021\\\/09\\\/Rugute_logo-b.svg\",\"width\":585,\"height\":583,\"caption\":\"Labdaros ir paramos fondas \u201eRugut\u0117\u201c\"},\"image\":{\"@id\":\"https:\\\/\\\/rugute.lt\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/rugute\\\/\",\"https:\\\/\\\/x.com\\\/rugute\",\"https:\\\/\\\/www.instagram.com\\\/rugute.lt\\\/\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/rugute\",\"https:\\\/\\\/www.youtube.com\\\/user\\\/Rugute\\\/videos\",\"https:\\\/\\\/lt.wikipedia.org\\\/wiki\\\/Rugut\u0117\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos - Labdaros ir paramos fondas \u201eRugut\u0117\u201c","description":"Vaik\u0173 mink\u0161t\u0173j\u0173 audini\u0173 sarkomos \u2013 tai grup\u0117 navikini\u0173 susirgim\u0173, kuomet piktybin\u0117s l\u0105stel\u0117s ima nevaldomai daugintis...","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/rugute.lt\/en\/informacija\/piktybiniai-navikai\/sarkomos\/","og_locale":"en_GB","og_type":"article","og_title":"Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos - Labdaros ir paramos fondas \u201eRugut\u0117\u201c","og_description":"Vaik\u0173 mink\u0161t\u0173j\u0173 audini\u0173 sarkomos \u2013 tai grup\u0117 navikini\u0173 susirgim\u0173, kuomet piktybin\u0117s l\u0105stel\u0117s ima nevaldomai daugintis...","og_url":"https:\/\/rugute.lt\/en\/informacija\/piktybiniai-navikai\/sarkomos\/","og_site_name":"Labdaros ir paramos fondas \u201eRugut\u0117\u201c","article_publisher":"https:\/\/www.facebook.com\/rugute\/","article_modified_time":"2022-01-12T07:51:06+00:00","og_image":[{"width":2000,"height":646,"url":"https:\/\/rugute.lt\/wp-content\/uploads\/2019\/01\/rugute_logo_uzrasas.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_site":"@rugute","twitter_misc":{"Estimated reading time":"7 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":["WebPage","MedicalWebPage"],"@id":"https:\/\/rugute.lt\/informacija\/piktybiniai-navikai\/sarkomos\/","url":"https:\/\/rugute.lt\/informacija\/piktybiniai-navikai\/sarkomos\/","name":"Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos - Labdaros ir paramos fondas \u201eRugut\u0117\u201c","isPartOf":{"@id":"https:\/\/rugute.lt\/#website"},"datePublished":"2020-04-14T14:12:17+00:00","dateModified":"2022-01-12T07:51:06+00:00","description":"Vaik\u0173 mink\u0161t\u0173j\u0173 audini\u0173 sarkomos \u2013 tai grup\u0117 navikini\u0173 susirgim\u0173, kuomet piktybin\u0117s l\u0105stel\u0117s ima nevaldomai daugintis...","breadcrumb":{"@id":"https:\/\/rugute.lt\/informacija\/piktybiniai-navikai\/sarkomos\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/rugute.lt\/informacija\/piktybiniai-navikai\/sarkomos\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/rugute.lt\/informacija\/piktybiniai-navikai\/sarkomos\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Prad\u017eia","item":"https:\/\/rugute.lt\/"},{"@type":"ListItem","position":2,"name":"Informacija","item":"https:\/\/rugute.lt\/informacija\/"},{"@type":"ListItem","position":3,"name":"Piktybiniai navikai","item":"https:\/\/rugute.lt\/informacija\/piktybiniai-navikai\/"},{"@type":"ListItem","position":4,"name":"Mink\u0161t\u0173j\u0173 audini\u0173 sarkomos"}]},{"@type":"WebSite","@id":"https:\/\/rugute.lt\/#website","url":"https:\/\/rugute.lt\/","name":"Childhood Cancer Fund Rugut\u0117","description":"Parama vaikams sergantiems v\u0117\u017eiu","publisher":{"@id":"https:\/\/rugute.lt\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/rugute.lt\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"},{"@type":"Organization","@id":"https:\/\/rugute.lt\/#organization","name":"Childhood Cancer Fund Rugut\u0117","url":"https:\/\/rugute.lt\/","logo":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/rugute.lt\/#\/schema\/logo\/image\/","url":"https:\/\/rugute.lt\/wp-content\/uploads\/2021\/09\/Rugute_logo-b.svg","contentUrl":"https:\/\/rugute.lt\/wp-content\/uploads\/2021\/09\/Rugute_logo-b.svg","width":585,"height":583,"caption":"Labdaros ir paramos fondas \u201eRugut\u0117\u201c"},"image":{"@id":"https:\/\/rugute.lt\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/rugute\/","https:\/\/x.com\/rugute","https:\/\/www.instagram.com\/rugute.lt\/","https:\/\/www.linkedin.com\/company\/rugute","https:\/\/www.youtube.com\/user\/Rugute\/videos","https:\/\/lt.wikipedia.org\/wiki\/Rugut\u0117"]}]}},"_links":{"self":[{"href":"https:\/\/rugute.lt\/en\/wp-json\/wp\/v2\/pages\/3865","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rugute.lt\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/rugute.lt\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/rugute.lt\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/rugute.lt\/en\/wp-json\/wp\/v2\/comments?post=3865"}],"version-history":[{"count":0,"href":"https:\/\/rugute.lt\/en\/wp-json\/wp\/v2\/pages\/3865\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/rugute.lt\/en\/wp-json\/wp\/v2\/pages\/3842"}],"wp:attachment":[{"href":"https:\/\/rugute.lt\/en\/wp-json\/wp\/v2\/media?parent=3865"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}